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Roche will pay $200 million to license Dicerna Pharmaceuticals’ RNA interference (RNAi) drug candidate for hepatitis B virus (HBV). Dicerna could also earn up to $1.5 billion in future payments for the molecule, which is in a Phase I clinical trial. The program will complement Roche’s experimental small-molecule and antisense oligonucleotide HBV treatments. Other companies developing RNAi therapies for HBV include Johnson & Johnson and Vir Biotechnology.
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