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Drug Discovery

858 Therapeutics raises $60 million

by Ryan Cross
September 24, 2021 | A version of this story appeared in Volume 99, Issue 35
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858 Therapeutics has launched with $60 million in series A financing to develop small-molecule cancer drugs. The San Diego-based start-up also acquired Gotham Therapeutics for an undisclosed sum. Gotham launched in 2018 to develop drugs based on epitranscriptomics, the study of chemical modifications to RNA. Gotham’s lead program is a drug that targets METTL3, an RNA-modifying enzyme that is elevated in some cancers. 858 hopes to advance that program into clinical trials by 2023.

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