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Drug Discovery
Covalent drugs go from fringe field to fashionable endeavor
Designing molecules that make bonds with their biological targets is in vogue
by Bethany Halford
November 9, 2020
| A version of this story appeared in
Volume 98, Issue 43
Credit: RCSB PDB/Yang H. Ku | The drug ibrutinib makes a covalent bond to Bruton's tyrosine kinase, an important cancer target.
The power is now in your (nitrile gloved) hands
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