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Drug Discovery
Merck signs a protein-degrader deal
by Shi En Kim
April 10, 2023
| A version of this story appeared in
Volume 101, Issue 12
The Austrian firm Proxygen has signed a collaboration and licensing agreement with Merck & Co. to discover and develop molecular glue degraders against multiple therapeutic targets. Unlike typical inhibitor drugs, molecular glue degraders work by eliminating disease-related proteins altogether. The Vienna-based start-up will receive up-front and milestone payments of up to $2.55 billion from Merck, and it is eligble for future royalties.
Chemical & Engineering News
ISSN 0009-2347
Copyright © 2024 American Chemical Society
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