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Drug Discovery

Nuvalent raises $50 million for drug-resistant cancer

by Ryan Cross
February 6, 2021 | A version of this story appeared in Volume 99, Issue 5
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Nuvalent has raised $50 million in series A financing from Deerfield Management to develop small-molecule kinase inhibitors for people whose tumors have developed resistance to existing kinase inhibitors. Nuvalent plans to start a clinical trial of its lead candidate, a ROS1 inhibitor, in non-small-cell lung carcinoma in the second half of 2021. It is also planning a clinical trial of its ALK inhibitor in 2022. Harvard University chemical biologist and organic chemist Matthew Shair founded Nuvalent with Deerfield in 2017.

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