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Drug Discovery

Roche and Jnana sign SLC transporter pact

by Lisa M. Jarvis
July 25, 2020 | A version of this story appeared in Volume 98, Issue 29
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Roche will pay Boston-based Jnana Therapeutics $40 million up front as part of a drug discovery pact that spans targets relevant in immunology and neuroscience. Stuart Schreiber and Ramnik Xavier, scientists at Broad Institute of MIT and Harvard, founded Jnana in 2017 to develop small molecules that target members of a family of 450 proteins, called solute carriers (SLC), that shuttle metabolites in and out of cells.

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