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Merck & Co. will acquire Acceleron Pharma for $11.5 billion to expand its cardiovascular disease portfolio. Acceleron is developing sotatercept, which is in multiple Phase 3 clinical trials for pulmonary arterial hypertension, a rare blood vessel disorder. Sotatercept is a recombinant fusion protein that traps ligands of the transforming growth factor-β superfamily of proteins. Merck will also share in profits of Acceleron’s anemia drug Reblozyl, which it is developing with Bristol Myers Squibb.
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