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Neuroscience

Expansion raises $80 million to drug RNA

by Ryan Cross
October 1, 2021 | A version of this story appeared in Volume 99, Issue 36
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Expansion Therapeutics has raised $80 million in series B financing to develop small-molecule drugs that target RNA. The start-up is based on the work of its founder, Scripps Research chemist Matthew Disney, who discovered compounds targeting repetitive sequences of RNA that cause myotonic dystrophy type 1, a genetic muscle disease. Expansion Therapeutics is now developing drugs for that condition and multiple neurodegenerative diseases, including amyotrophic lateral sclerosis, frontotemporal dementia, and several tauopathies.

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