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The Swiss start-up Noema Pharma has raised about $60 million in series A financing to develop four experimental drugs, licensed from Roche, for rare neurological diseases. Noema will test the lead candidate, an mGluR5 inhibitor, in Phase 2b trials to stop seizures in tuberous sclerosis complex and relieve severe pain in trigeminal neuralgia. Roche previously tested the drug for fragile X syndrome and depression with disappointing results. Noema will also test a PDE10A inhibitor in a Phase 2b trial of Tourette’s syndrome.
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