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Oncology

Amgen to acquire Five Prime for $1.9 billion

by Ryan Cross
March 12, 2021 | A version of this story appeared in Volume 99, Issue 9
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Amgen will acquire the cancer drug firm Five Prime Therapeutics for about $1.9 billion. Five Prime’s lead drug candidate, bemarituzumab, is an antibody that targets a mutant form of fibroblast growth factor receptor called FGFR2b. The mutant receptor is abundant in some cancers, where it promotes the growth of tumors. Bemarituzumab has already been tested in a Phase 2 study of people with gastric cancers, but Amgen says the antibody could also be useful in other cancers driven by FGFR2b.

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