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AstraZeneca will pay $1 billion, plus potential milestone payments, to develop DS-1062, a cancer-fighting antibody-drug conjugate (ADC) from Daiichi Sankyo. The deal is the second between the two firms. In March 2019, AstraZeneca paid $1.35 billion to develop Enhertu, another Daiichi ADC. Both molecules use Daiichi’s DXd technology for attaching an antibody to a cytotoxic agent with a tetrapeptide linker designed to be broken down by enzymes made by tumor cells.
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