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Oncology

Gilead invests in cancer immunology-focused Tizona

by Lisa M. Jarvis
July 25, 2020 | A version of this story appeared in Volume 98, Issue 29
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Gilead Sciences is paying $300 million for a 49.9% stake in San Francisco–based Tizona Therapeutics. The centerpiece of the deal is TTX-080, an antibody that targets the immune checkpoint protein HLA-G; it is expected to begin clinical studies in solid cancers this quarter. Gilead can acquire the rest of the firm for up to $1.25 billion after seeing data from Phase Ib studies. The deal does not include TTX-030, an anti-CD39 antibody that Tizona licensed to AbbVie for $105 million last year.

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