Already have an ACS ID? Log in
Renew your membership, and continue to enjoy these benefits.
Already an ACS Member? Log in here
Choose the membership that is right for you. Discounts will be applied automatically at checkout.
Enjoy these benefits no matter which membership you pick.
Carmen Sivakumaren collected these colorful solutions in test tubes as they flowed off a silica gel column. The graduate student at Harvard University and Dana-Faber Cancer Institute was looking for a specific product of a nucleophilic substitution reaction she ran between an indole and a trichloropyrimidine. When chemists run a reaction mixture through a silica column, molecules exit the column at different times depending on their polarity, allowing them to isolate their desired product. Because Sivakumaren’s reaction produced strongly colored by-products, she could spot groups of test tubes that held different by-products with the naked eye. Eventually, Sivakumaren found her product, which ironically was a white solid.
Submitted by Carmen Sivakumaren
Do science. Take pictures. Win money. Enter our photo contest here.
Related C&EN Content:
Sign up for C&EN's must-read weekly newsletter
This article has been sent to the following recipient: