Volume 90 Issue 6 | p. 30 | Concentrates
Issue Date: February 6, 2012

Microscope Peers Into A Mouse’s Brain

Superresolution fluorescence technique enables scientists to track neuron morphology in a live animal
Department: Science & Technology
News Channels: Analytical SCENE, Biological SCENE
Keywords: superresolution microscopy, STED, brain, neuron

Researchers have used the superresolution fluorescence microscopy method known as STED, or stimulated emission depletion, to acquire images of a neuron inside the brain of a living adult mouse (Science, DOI: 10.1126/science.1215369). Katrin I. Willig and Stefan W. Hell at the Max Planck Institute for Biophysical Chemistry, in Göttingen, Germany, and coworkers used a STED microscope to shine beams of light through a glass-sealed . . .

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