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Neuroscience
Why lecanemab’s success spells the revival of small-molecule Alzheimer’s treatments
Unlike bulky biologics, small molecules can make Alzheimer’s treatments cheap, convenient to administer, and widely accessible, experts say
by Shi En Kim
March 12, 2023
| A version of this story appeared in
Volume 101, Issue 9
Credit: Science Source | Positron-emission tomography (PET) scans of human brains without Alzheimer’s disease (top row) and those affected by it (bottom row). One hallmark of the disease is the accumulation of amyloid plaques, denoted in red. These plaques are thought to drive cognitive decline.
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