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Astellas Pharma has signed a research pact with Pandion Therapeutics, a start-up in Cambridge, Massachusetts, developing bispecific antibodies for pancreatic autoimmune diseases, particularly type 1 diabetes. Pandion is developing drugs that target specific tissues and simultaneously turn down aberrant immune cell responses that cause autoimmune disease. Astellas will pay Pandion up to $45 million up front and potentially more than $750 million in milestone payments.
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