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Pharmaceutical Chemicals

Manus Bio gets Gates grant for artemisinin

by Melody M. Bomgardner
April 9, 2021 | A version of this story appeared in Volume 99, Issue 13
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The chemical structure of artemisinin is shown.

Manus Bio has received an undisclosed sum from the Bill and Melinda Gates Foundation to develop a cost-effective way to produce artemisinin, a malaria treatment, via fermentation. The foundation has set a target cost for the treatment of $100 per kilogram. Artemisinin is currently derived from plants; Manus, one of C&EN’s 10 Start-Ups to Watch in 2018, will use engineered microbes and enzymes to produce the compound. Manus also received a grant from the Gates foundation in 2018.

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