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Infectious disease

Atea’s COVID-19 antiviral fails in Phase 2 trials

by Megha Satyanarayana
October 23, 2021 | A version of this story appeared in Volume 99, Issue 39
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Atea Pharmaceuticals’ oral COVID-19 drug, AT-527, failed its Phase 2 clinical trial, the company says. In people with mild to moderate COVID-19, the antiviral showed no difference in viral load compared with the placebo group, though it did show some reduction in viral load in people at high risk of severe infection. As a result, Atea and Roche, which are jointly developing AT-527, are considering changes to a planned Phase 3 trial.

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