September 6, 2004 Issue | Chemical & Engineering News
 
Copyright © 2004 American Chemical Society
 

September 6, 2004 Issue

Volume 82, Issue 36
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September 6, 2004 Issue, Vol. 82 | Iss. 36
Suzuki-coupling chemistry takes hold in commercial practice, from small-scale synthesis of screening compounds to industrial production of active ingredients
By A. MAUREEN ROUHI, C&EN WASHINGTON
(pp. 49-58)
Features
Science & Technology
Iron phosphine molecular gyroscopes synthesized by ring-closing metathesis 
Science & Technology
Chicken feathers are being transformed into films, composites, plastics, and roofing material (pp. 36-39)
Back Issues
 

Cover Story: FINE CHEMICALS

VARIATIONS ON THE COUPLING THEME
Chemistries similar to Suzuki coupling are multiplying access to synthetic targets
(pp. 59-61)
WHEN COOPERATIVE RIVALRY WORKS
Two fine chemicals companies separately but cooperatively bring key technology to market
(pp. 62-64)
OUTSIDE-THE-BOX APPROACH TO BIARYLS
By not using a Suzuki coupling, seasoned process chemist dramatically reduces cost of synthesis
(pp. 66-67)
 

News of the Week

FALLEN STAR

Genesis space capsule containing solar wind crashes to Earth
(p.9)

FULLY ENCLOSED MOLECULAR ROTORS

Iron phosphine molecular gyroscopes synthesized by ring-closing metathesis
(p.11)

INHIBITORS TARGET KEY TB ENZYME

Iminosugars may provide leads for new class of tuberculosis drugs
(p.12)

NALCO FILES TO GO PUBLIC

Owners want to raise $800 million, seek New York Stock Exchange listing
(p.12)

EUROPEANS CHART NEW PATHS FOR R&D

Akzo Nobel, UCB reorganize drug research units
(p.13)

NIH WEIGHS OPEN ACCESS

Agency meets with scientists, public interest groups on draft policy
(p.14)

DOW, BASF TO BUILD PROPYLENE OXIDE

Companies mark success in process with plans for plant in Belgium
(p.15)

RDX LINKS RUSSIAN CRASHES

Powerful explosive found in the debris of two planes that crashed
(p.15)
 

Departments

Business

Gene silencing with RNAi might offer novel therapeutics and help with nondruggable targets
(pp. 18-23)
Chemical industry CIOs defend their role as strategists in the post-cost-cutting era
(pp. 24-29)
New plant key to 'Verbund' strategy of integrated production of fine chemicals, vitamins
(p.30)
The chemical industry is coping, but high oil and natural gas prices could slow it down
(p.32)

Science & Technology

Chemistries similar to Suzuki coupling are multiplying access to synthetic targets
(pp. 59-61)
Two fine chemicals companies separately but cooperatively bring key technology to market
(pp. 62-64)
By not using a Suzuki coupling, seasoned process chemist dramatically reduces cost of synthesis
(pp. 66-67)
Suzuki-coupling chemistry takes hold in commercial practice, from small-scale synthesis of screening compounds to industrial production of active ingredients
(pp. 49-58)
Chicken feathers are being transformed into films, composites, plastics, and roofing material
(pp. 36-39)
Long eclipsed by metals, small-molecule organic catalysts are back and here to stay
(pp. 41-45)
Focus groups with 10- to 14-year-olds shed light on their attitudes about chemists and chemistry