Copyright © 2014 American Chemical Society
 

December 22, 2014 Issue

Volume 92, Issue 51
09251-cov-cover
December 22, 2014 Issue, Vol. 92 | Iss. 51
By Amanda Yarnell
(p.15)
Features
Science & Technology
Biology: During egg fertilization, bursts of cations release from near the cell’s membrane (p.8)
Back Issues
 
Iridium Dressed To The Nines
Periodic Table: IrO4+ is the first molecule with an element in the +9 oxidation state
(p.16)
Hydrogen Bonds: Real Or Surreal?
Microscopy: Bonds imaged by AFM last year may be an artifact of the technique, leaving the discovery in question
(p.17)
More Graphene Surprises
Material Science: Researchers are shocked to find that the thin carbon sheet can decompose and can conduct protons
(p.17)
Add Salt To Taste For Negishi Cross-Couplings
Chemists find that salt additives affect aryl- and alkylzinc reagents differently
(p.18)
Reaction Modeling Enhances Experiment
Computational Chemistry: Ab initio nanoreactor finds previously undetected products and mechanisms
(p.18)
Bacteria Accept Expanded Genetic Code
Synthetic Biology: Researchers put DNA made from three base pairs—instead of the usual two—into living cells
(p.19)
High-Purity Nanotubes Grown From Seed
Nanotechnology: Two new routes create specific types of single-walled carbon nanotubes with high purity
(p.19)
Chiral Catalyst Leads To New Stereopolymer
Polymer Science: Process marries right- and left-handed polymer chains to create a stereocomplex material with commodity potential
(p.20)
Electron Microscopy Alone Reveals Protein Machine’s Structure
Structural Biology: Technique gives first glimpse of mitochondrial ribosome at near-atomic resolution
(p.20)
Perovskite Solar Cells Gain More Ground
Photovoltaics: Scientists continue to improve the low-cost sun-catching materials
(p.21)
Winds Calm For The Shale Gale
Petrochemicals: Cost overruns and lower oil prices became headwinds for U.S. chemical makers
(p.22)
Neonicotinoids Under Fire
Pollinators: Pesticides linked to bee deaths
(p.23)
Tainted Drinking Water In West Virginia
Water Pollution: Chemical leak tainted drinking water in West Virginia with substance used to process coal
(p.23)
Lab Death Legal Cases Resolved
Felony charges against the University of California and chemistry professor Patrick Harran dropped in exchange for safety program and community service
(p.24)
Scientists Respond To Ebola Crisis
Drug Development: Outbreak in West Africa sparked flurry of activity to combat deadly virus
(p.25)
Update Of Chemical Law Stalls
Partisan gridlock snarled Toxic Substances Control Act reform
(p.25)
EPA Moves To Cut CO2
Climate Change: Move provoked coal supporters but gave push to treaty talks
(p.26)
Nobel Prizes At A Glance
Here’s who scored a coveted ticket to Stockholm
(p.26)
U.S. Destroys Syria’s Chemical Weapons
Landmark Mission: Regime’s most lethal warfare agents neutralized at sea
(p.27)
Chemical Jobs And Salaries
Economy: U.S. employment picks up, but wages stalled; overseas weakness persisted
(p.28)
Chinese Citizens Protested -Xylene
Environmental Dispute: Clash over plant making polyester intermediate turned violent
(p.28)
Chemical Deals Engine Revs Up
Strategy: Mergers and acquisitions activity increased in 2014
(p.29)
Structure Error Caused Cancer Drug Mix-Up
Drug Discovery: An old mistake led two companies to pursue development and patenting of the same promising anticancer compound
(p.30)
Trade-Secret Struggles Abound
Intellectual Property: China figured prominently in two theft accusations
(p.30)
A Blossoming Of Agrochemical Deals
Crop Protection: Consolidation hit off-patent agricultural chemical sector
(p.31)
Europe’s Chemical Makers Struggle
Competitiveness: Slack demand along with high energy and raw material prices made it a difficult year
(p.31)
Activist Funds Shape Chemical Firms
Finance: Hedge funds gave voice to disgruntled shareholders
(p.32)
States Step Up On Chemical Regulations
State Laws: Legislatures acted on triclosan, microbeads, and flame retardants
(p.32)
American Chemical Society Selects New Leaders
Transitions: President, CEO, and journal editors-in-chief will assume posts in 2015
(p.33)
Shake-Ups In The Sweetener Business
Food Ingredients: Low-cost imports of widely used noncaloric sweeteners forced makers to cut back
(p.33)
Congress Renews Antiterrorism Program
Antiterrorism: New law extended security requirements for chemical facilities
(p.34)
Food Babe Strikes Again
Chemophobia: A blogger’s growing voice has food makers acting, even if her science is shaky
(p.34)
DESI Turns 10
Instrumentation: Desorption electrospray ionization has taken mass spectrometry to new places
(p.38)
Fast TB Treatment Slow To Advance
Drug Development: Much heralded as a tuberculosis-fighting compound, bedaquiline’s impact remains to be seen
(p.39)
Sneaking A Look At Sugars—Inside Cells
Bioorthogonal Chemistry: Carbohydrate labeling strategy has come a long way in 10 years
(p.40)
 

News of the Week

Chemical Output Seen Rising In Coming Year

Economy: Outlook is robust for the U.S., tepid for Europe
(p.5)

New Route To Adipic Acid Avoids Nitrous Oxide Production


Synthesis: Process provides another option for making nylon precursor without production of potent greenhouse gas
(p.6)

University Of California Settles Charges That Researcher Got Overlapping Federal Grants

Investigation: $500,000 settlement allows UC Davis scientist to continue receiving funding
(p.6)

Radical Reaction Forms Previously Inaccessible Alkene Coupling Products

Organic Synthesis: New iron-based catalyst links reactants, avoids heteroatom byproducts
(p.7)

Indian Court Upholds Breaking Of Bayer Patent

Intellectual Property: Supreme Court decision is likely to increase Western pressure on India to tighten patent laws
(p.8)

Of Zinc And Making Babies

Biology: During egg fertilization, bursts of cations release from near the cell’s membrane
(p.8)
 

Departments

09251-cover12-constructioncxd

Business

Petrochemicals: Cost overruns and lower oil prices became headwinds for U.S. chemical makers
(p.22)
Strategy: Mergers and acquisitions activity increased in 2014
(p.29)
Competitiveness: Slack demand along with high energy and raw material prices made it a difficult year
(p.31)
Crop Protection: Consolidation hit off-patent agricultural chemical sector
(p.31)
Food Ingredients: Low-cost imports of widely used noncaloric sweeteners forced makers to cut back
(p.33)
Intellectual Property: China figured prominently in two theft accusations
(p.30)
Chemophobia: A blogger’s growing voice has food makers acting, even if her science is shaky
(p.34)
Economy: U.S. employment picks up, but wages stalled; overseas weakness persisted
(p.28)
Finance: Hedge funds gave voice to disgruntled shareholders
(p.32)

ACS News

Transitions: President, CEO, and journal editors-in-chief will assume posts in 2015
(p.33)
09251-cover35-GMOCXD

Government & Policy

Drug Development: Outbreak in West Africa sparked flurry of activity to combat deadly virus
(p.25)
Partisan gridlock snarled Toxic Substances Control Act reform
(p.25)
Pollinators: Pesticides linked to bee deaths
(p.23)
Landmark Mission: Regime’s most lethal warfare agents neutralized at sea
(p.27)
Environmental Dispute: Clash over plant making polyester intermediate turned violent
(p.28)
Climate Change: Move provoked coal supporters but gave push to treaty talks
(p.26)
Antiterrorism: New law extended security requirements for chemical facilities
(p.34)
Water Pollution: Chemical leak tainted drinking water in West Virginia with substance used to process coal
(p.23)
State Laws: Legislatures acted on triclosan, microbeads, and flame retardants
(p.32)
09251-cover13-shericxd

Science & Technology

Felony charges against the University of California and chemistry professor Patrick Harran dropped in exchange for safety program and community service
(p.24)
Drug Development: Much heralded as a tuberculosis-fighting compound, bedaquiline’s impact remains to be seen
(p.39)
Instrumentation: Desorption electrospray ionization has taken mass spectrometry to new places
(p.38)
Bioorthogonal Chemistry: Carbohydrate labeling strategy has come a long way in 10 years
(p.40)
Material Science: Researchers are shocked to find that the thin carbon sheet can decompose and can conduct protons
(p.17)
Computational Chemistry: Ab initio nanoreactor finds previously undetected products and mechanisms
(p.18)
Microscopy: Bonds imaged by AFM last year may be an artifact of the technique, leaving the discovery in question
(p.17)
Structural Biology: Technique gives first glimpse of mitochondrial ribosome at near-atomic resolution
(p.20)
Synthetic Biology: Researchers put DNA made from three base pairs—instead of the usual two—into living cells
(p.19)
Chemists find that salt additives affect aryl- and alkylzinc reagents differently
(p.18)
Nanotechnology: Two new routes create specific types of single-walled carbon nanotubes with high purity
(p.19)
Photovoltaics: Scientists continue to improve the low-cost sun-catching materials
(p.21)
Periodic Table: IrO4+ is the first molecule with an element in the +9 oxidation state
(p.16)
Drug Discovery: An old mistake led two companies to pursue development and patenting of the same promising anticancer compound
(p.30)
Polymer Science: Process marries right- and left-handed polymer chains to create a stereocomplex material with commodity potential
(p.20)
Here’s who scored a coveted ticket to Stockholm
(p.26)
(pp. 36-37)