Copyright © 2017 American Chemical Society
July 3, 2017 Cover
Volume 95, Issue 27
Volume 95, Issue 27
The first approval of a tissue-agnostic treatment signals change in how oncology drugs are tested and used
Credit: Yang H. Ku/C&EN/Shutterstock/Frank Ramspott/iStock.com
» Full Article
July 3, 2017 Issue
Volume 95, Issue 27
July 3, 2017 Issue, Vol. 95 | Iss. 27
The first approval of a tissue-agnostic treatment signals change in how oncology drugs are tested and used
(pp. 26-30)
Features
Science & Technology
Researchers analyze the odors wafting off drinking water to help make it stink-free (pp. 16-19)
Science & Technology
Fireworks have thrilled crowds for centuries; now science is working to make their fallout more environmentally friendly (pp. 24-25)
News of the Week
Lawsuits progress against Sci-Hub
Distributor of pirated papers loses to Elsevier, faces new suit from American Chemical Society
(p.5)How plants release their fragrant molecules
Petunias actively pump out volatile odor compounds with the help of protein transporters, study finds
(p.6)Nutmeg compound is cooler than menthol
Neolignan molecule could help prolong menthol’s icy effect
(p.6)Chemists discover biology’s version of the Friedel-Crafts alkylation
Newly detected enzyme alkylates aromatic rings during biosynthesis of cylindrocyclophanes
(p.7)The first herpes capsid at atomic resolution
At 3.9 Å resolution, structure reveals how human cytomegalovirus capsids withstand pressure caused by packing in loads of DNA
(p.7)Success for Merck’s anacetrapib
The CETP inhibitor surprises with positive Phase III results
(p.11)Syngenta looks ahead after ChemChina deal
With backing from new owner, Swiss firm looks to boost sales to China
(p.11)California to list glyphosate as a carcinogen
Monsanto challenges state’s move as it faces new false claims lawsuit
(p.14)More evidence shows neonicotinoids harm bees
Large field studies show that effects depend on multiple factors
(p.14)Departments
Business
With the help of chemical makers, U.S. energy companies are reducing the cost of extracting oil from the ground
(pp. 20-21)ACS News
Government & Policy
Science & Technology
Fireworks have thrilled crowds for centuries; now science is working to make their fallout more environmentally friendly
(pp. 24-25)
Researchers analyze the odors wafting off drinking water to help make it stink-free
(pp. 16-19)
The first approval of a tissue-agnostic treatment signals change in how oncology drugs are tested and used
(pp. 26-30)
Biotechnology has moved on from pharmaceuticals to agriculture, creating new opportunities for chemists
(pp. 22-23)
Rapid cutting enables study of wound healing in individual cells
(p.8)
A six-year comparison of organic versus conventional onions shows higher levels of phytochemicals thought to promote health
(p.8)
Continuous process makes a chiral homopropargyl β-amino alcohol building block in just two steps
(p.8)
Delocalized seven-carbon ring system facilitates metal-free batch and flow acetalization reactions
(p.9)
Yeast-based biosensors could also be extended to sense viruses and bacteria
(p.9)
Light-responsive material could eject sand and dust from self-cleaning solar panels
(p.9)
La molécula de neolignano podría ayudar a prolongar el efecto helado del mentol
(p.6)