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March 24, 2014 Cover
Volume 92, Issue 12
Human genetic studies point drugmakers to a specific sodium channel target for painkillers
Cover image:
Credit:
Changing The Channel
Human genetic studies point drugmakers to a specific sodium channel target for painkillers
Budget Blues
President Obama’s 2015 R&D budget request doesn’t keep up with inflation
Living Up To The Process Challenge
In a typical day, process chemists select reagents, pore over synthetic routes, think about safety, and manage costs
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Process Chemistry: Recasting Regulatory Strategies To Enable Green Chemistry
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Restructuring For Real In Japan
Pressured by high costs and a shrinking home market, producers are getting serious about slashing unprofitable businesses
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Dynamics Determine Enzyme Selectivity
Biosynthetic protein may steer a reaction after the transition state to home in on a single natural product
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Science Concentrates
Taking Cues From Nature En Route To Paclitaxel
ACS Meeting News: Synthesis of an intermediate along the way to the cancer drug opens avenues to novel analogs
