January 8, 2018 Issue | Chemical & Engineering News
 
Copyright © 2018 American Chemical Society
 

January 8, 2018 Issue

Volume 96, Issue 2
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January 8, 2018 Issue, Vol. 96 | Iss. 2
Economic health across the globe should mean a good 2018 for the world chemical industry
By Business Department
(p.27)
Features
Science & Technology
The massive molecule has been poisoning home aquarium owners (pp. 12-14)
Business
A spike in FDA letters citing inadequate data quality at drug plants puts the spotlight on software—and the people who use it (pp. 15-17)
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News of the Week

China restricts imports of plastic trash

Move upsets recycling programs worldwide but may lead to better waste management
(p.3)

Stepping up gene synthesis

Emulsions allow multiple genes to be assembled simultaneously from pools of oligonucleotides
(p.4)

Scalable method to make tissue engineering material

New method produces 3-D-printable material with modifiable end groups
(p.5)

Carfilzomib linked to higher rates of cardiovascular problems

Analysis of clinical trial data shows that patients taking cancer drug are twice as likely to experience adverse cardiac issues
(p.6)

Sulfones expand the reach of radical cross-couplings

New reagents offer streamlined synthesis of valuable fluorinated products
(p.6)

Ultrasound-bouncing bubbles help track bacteria in mice

Bacteria engineered with gas vesicles allow researchers to use ultrasound to image the microbes at higher resolutions and greater depths than before
(p.7)

Pfizer inks protein degradation deal with Arvinas

Worth up to $830 million, the multi-year pact will support the discovery of multiple small molecules
(p.8)

U.K. firm touts bacon breakthrough

Recipe uses fruit, spice extracts in place of cancer-linked nitrites
(p.8)

Expansion Therapeutics launches to target RNA with $55 million

Start-up will develop small molecules targeting RNA in the muscle-wasting disease myotonic dystrophy
(pp. 14-15)
 

Departments

09602-bus1-numbers

Business

A spike in FDA letters citing inadequate data quality at drug plants puts the spotlight on software—and the people who use it
(pp. 15-17)
The first company-sponsored clinical trials of the gene editing system will treat genetic blood diseases
(pp. 18-19)
Economic health across the globe should mean a good 2018 for the world chemical industry
(p.27)

ACS News

Recipients are honored for contributions of major significance to chemistry
(p.36)
Recipients are honored for contributions of major significance to chemistry
(pp. 36-51)
09602-scitech-zhangcxd-new

Science & Technology

Yuegang Zhang shares how novel cathode designs may bring lightweight batteries to market
(pp. 20-21)
The massive molecule has been poisoning home aquarium owners
(pp. 12-14)
Material can be woven into textiles that harvest energy from motion
(p.7)
The disaccharide trehalose makes certain strains of Clostridium difficile more deadly
(p.4)
Printed PDMS samples are stronger, stiffer, and less porous than ones made by conventional casting methods
(p.7)
Computer simulations predict a new light-activated catalyst could make the Haber-Bosch process obsolete
(p.7)
Renowned scientists offer their picks for unsung chemistries that just may change the world.
(pp. 22-25)

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