Copyright © 2016 American Chemical Society
June 6, 2016 Cover
Volume 94, Issue 23
Volume 94, Issue 23
After decades of failures, researchers see promise in fresh approaches to developing drugs that block cancer’s toughest target
Credit: Yang H. Ku/C&EN/Shutterstock
» Full Article
June 6, 2016 Issue
Volume 94, Issue 23
June 6, 2016 Issue, Vol. 94 | Iss. 23
After decades of failures, researchers see promise in fresh approaches to developing drugs that block cancer’s toughest target
(pp. 28-33)
Features
Science & Technology
As the Volkswagen scandal showed, building fuel-efficient, low-emitting vehicles is no easy task (pp. 18-20)
Career & Employment
Chemistry professor turned patent attorney says there’s life after being denied tenure (p.27)
News of the Week
Atomic force microscopy takes home Kavli Prize
Gerd Binnig, Christoph Gerber, and Calvin Quate will share foundation's $1 million nanoscience prize
(p.5)Microplastics stunt fish growth and alter behavior
Exposure study of perch embryos and larvae adds to growing concern over the ocean pollutants
(p.7)Virus helps unmask anticancer drug to attack brain tumors
Phase I clinical trial results show promise for new glioma treatment
(p.7)An ion-selective detector made of paper
Disposable device that can be used in the field consists of membranes and printed components
(p.8)Recreational drug kratom hits the same brain receptors as strong opioids
Chemists study the neurochemistry of alkaloids from the Mitragyna plant
(p.8)Jazz Pharmaceuticals to buy Celator Pharmaceuticals
Deal worth $1.5 billion brings promising nanoparticle-based cancer drug
(p.12)Specialties maker Vertellus files for bankruptcy
Dynamic chemical firm succumbs to stiff competition in China
(p.12)Thermo Fisher to acquire FEI
Instrument giant fills a gap in its portfolio with $4.2 billion electron microscopy acquisition
(p.13)U.K. fractures over fracking
England approves first gas well in four years, but Scotland resists
(p.13)European science ministers call for open access
By 2020, publications of publicly funded research are to be freely available in EU, but details are unclear
(p.16)Departments
Business
After decades of failures, researchers see promise in fresh approaches to developing drugs that block cancer’s toughest target
(pp. 28-33)
As a long-used curative for urethane elastomers faces a ban in Europe, polyurethane suppliers look at alternatives
(pp. 25-26)
New companies still face many hurdles, but increased government support and higher risk appetite make it a bit easier to launch a start-up in Japan
(pp. 21-22)Concentrates
(pp. 14-15)
(pp. 14-15)- Dow completes purchase of Dow Corning
- OpenGate to acquire zinc chemicals business
- Bolivia will get first polymer plant
- SABIC considers Chinese project
- Covestro’s on the (soccer) ball
- Ube buys rights to trimethylindium
- Stem attracts funds for battery systems
- Gevo considers selling itself
- Carbogen expands in Switzerland
- Iceni to repurpose Merck’s cilengitide
- Sun Pharma gets U.S. subpoena
- Novartis and Akzo grow R&D in China
- Business Roundup
Science & Technology
‘The Poisoner’s Handbook’ writer talks about the beauty of chemistry and why she wants people to know more about it
(pp. 23-24)
As the Volkswagen scandal showed, building fuel-efficient, low-emitting vehicles is no easy task
(pp. 18-20)
Un estudio sobre la exposición a los microplásticos en embriones y larvas de perca aumenta la preocupación sobre los contaminantes oceánicos
(p.7)Concentrates(pp. 9-10)
(pp. 9-10)- DNA origami bends into metamaterial fold
- Stick insects stole digestive enzyme genes from their microbiome
- Arenes selectively nitrated at meta position
- New oxidation states for neptunium organometallic complexes
- Parmesan test can detect cheesy imposters
- Decked-out thiophene adds versatility to semiconducting polymers
Career & Employment
Chemistry professor turned patent attorney says there’s life after being denied tenure
(p.27)