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June 3, 2019 Cover

Volume 97, Issue 22

The cellular housecleaning and self-renewal process is implicated in neurodegenerative diseases, cancer, and more. Can biotech companies walk the fine line between boosting and inhibiting autophagy to treat disease without causing it?

Cover image:Autophagy, the process of cellular housecleaning and self-renewal, is implicated in neurodegenerative diseases, cancer, and more. Can biotech companies walk the fine line between boosting and inhibiting autophagy to treat disease without causing it?

Credit: Chris Gash

Full Article

Autophagy: Drugging the yin and yang of the cell

The cellular housecleaning and self-renewal process is implicated in neurodegenerative diseases, cancer, and more. Can biotech companies walk the fine line between boosting and inhibiting autophagy to treat disease without causing it?

  • From our archives: An essay on selenium, by Liu Tungsheng

    To celebrate the International Year of the Periodic Table, C&EN is re-releasing its favorite essays from a special 2003 collectors’ issue celebrating the elements

  • US hemp boom creates chaos

    Companies struggle with varying state laws, lack of federal guidance

  • Career Ladder: Anne Mallaband

    This English chemist worked in industry before moving to academia and European science policy

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