
June 19, 2017 Cover
Volume 95, Issue 25
Volume 95, Issue 25
With the bar-coding technology, drugmakers leverage the chemistry of large numbers
Credit: C&EN
» Full Article
June 19, 2017 Issue
Volume 95, Issue 25
June 19, 2017 Issue, Vol. 95 | Iss. 25
With the bar-coding technology, drugmakers leverage the chemistry of large numbers
(pp. 28-33)
Features

Science & Technology
Purifying chemicals without heat would go a long way toward reducing global energy consumption and pollution (pp. 18-21)

Science & Technology
Peter Hore explains how he and others are tackling the magnetoreception mystery (pp. 22-23)
News of the Week
Green chemistry efforts honored
2017 Green Chemistry Challenge Awards hail streamlined syntheses, dye-free printing, and more
(p.5)Flow chemistry reaches manufacturing milestone
Lilly chemists make chemotherapy drug candidate in a multistep continuous flow process using current Good Manufacturing Practices
(p.7)Fly-egg profiling method reveals a corpse’s ‘time of death’ faster
Rapid technique for classifying insect eggs on corpses expedites time-of-death estimations
(p.7)Un método analiza huevos de moscas y revela el momento de la defunción más rápido
Una rápida técnica de clasificación de huevos de insectos en cadáveres ayuda a estimar mejor la hora de la muerte
(p.7)FDA takes aim at opioid epidemic
Agency wants to pull opioid from market because it says the drug’s benefits don’t outweigh its risks
(p.8)Plastic solar cells: Now in a rainbow of colors
Dye molecule tailors the hue of organic solar cells without hindering performance
(p.8)Antibacterial molecule may discourage resistance
Agent blocks bacterial but not human RNA polymerase active site
(p.9)More moves with metathesis
Chemists swap substituents on C–S and C–P bonds
(p.9)PQ takes another shot at going public
Inorganic chemicals maker seeks listing on the New York Stock Exchange
(p.12)Thermo Fisher reveals first-of-its-kind clinical analyzer
Launch of easy-to-use system opens clinical market to traditional LC/MS makers
(p.12)Europe may call TiO2 a carcinogen
Inhalation studies in rats spark push for classification
(p.13)Ineos poised for major European expansion
Planned hikes in propylene and ethylene reflect strengthening market conditions
(p.13)U.S. National Institutes of Health backs off funding limits for researchers
Agency instead creates initiative to support early- and midcareer scientists
(p.16)U.S. Supreme Court ruling gives biosimilar drugs a boost
Companies can market generic biological medicines sooner
(p.16)U.S. National Academies give ARPA-E good grades
Program funding high-risk, early-stage energy research targeted for elimination by Trump
(p.17)Wind and solar combined surpass 10% of U.S. electricity generation
Contribution expected to drop during summer months
(p.17)Departments
Business
At executive gathering, low energy costs pleased but politics unnerved
(p.26)
New policies plus technology advances and energy availability bode well for turning around the industry
(pp. 24-25)Concentrates
(pp. 14-15)

- Arkema files complaint against Honeywell
- Eastman Chemical resigns from trade group
- New York biotech incubator opens
- Air Liquide places bets on start-ups
- Hexion changes Craigs
- PEF resin gets EU backing
- Citrine raises funds for materials design
- Heineken beer barge beats CO2
- Johnson Matthey teams with Intrexon
- Celgene in cancer deal with Dragonfly
- BARDA expands Basilea’s funding
- WuXi Biologics shares surge on first day of trading
- Business Roundup
ACS News
Government & Policy
Science & Technology
Peter Hore explains how he and others are tackling the magnetoreception mystery
(pp. 22-23)
With the bar-coding technology, drugmakers leverage the chemistry of large numbers
(pp. 28-33)
Purifying chemicals without heat would go a long way toward reducing global energy consumption and pollution
(pp. 18-21)Concentrates
(pp. 10-11)

- Modeling reduces nickel needed in catalytic reactions
- Mass spec imaging identifies tumor margins during brain surgery
- Jupiter is a big old planet
- Green synthesized biofuel meets auto standards
- Probes track vancomycin-induced cell wall changes
- Batteries with helical and serpentine shapes stand up to repeated stretching and bending
Career & Employment
Balancing career aspirations with family obligations
(p.27)