Copyright © 2013 American Chemical Society
June 17, 2013 Cover
Volume 91, Issue 24
Volume 91, Issue 24
After many disappointing studies, PARP inhibitors are finally showing promise as killers of cells already damaged by mutations
Credit: Shutterstock/C&EN
» Full Article
June 17, 2013 Issue
Volume 91, Issue 24
June 17, 2013 Issue, Vol. 91 | Iss. 24
After many disappointing studies, PARP inhibitors are finally showing promise as killers of cells already damaged by mutations
(pp. 13-18)
Features
Government & Policy
Radical restructuring proposed for federal science education funding has the community scrambling (pp. 25-28)
Science & Technology
Synthesis of lanthanide(II) compounds may lead to other chemical transformations (pp. 32-33)
News of the Week
High Court Nixes Gene Patents
Biotechnology: Naturally occurring genes can’t be owned, but synthetic gene material can be
(p.7)Neurons Counted In Adults
Neuroscience: Carbon dating measures birth of nerve cells in human brains
(p.8)U.S., China Agree On Refrigerants
Climate: Countries will work to curb manufacture of hydrofluorocarbons
(p.8)AstraZeneca Buys Pearl Therapeutics
Pharma: Acquisition adds lung drug candidate to AstraZeneca’s pipelinerebuilding campaign
(p.9)Minor Dust Mineral May Be Key Ice Seed
Atmosphere: Feldspars found to be good seed for ice crystals in clouds
(p.9)A Less Toxic Antifungal Agent
Medicinal Chemistry: Modified version of amphotericin B will drive search for effective analogs
(p.10)Bill Gates Backs Open Science Website ResearchGate
ResearchGate raises $35 million to mount challenge to traditional science publishing
(p.10)Cell’s Water Channel Gets A Close-Up
Structural Biology: High-resolution structure of aquaporin sheds light on function of water transporter
(p.11)Departments
Business
Transformation via new energy source will come gradually, chemical executives say
(p.22)
Herbicide is behind a U.S. firm’s purchase of a troubled pyridine plant in China
(p.23)
After many disappointing studies, PARP inhibitors are finally showing promise as killers of cells already damaged by mutations
(pp. 13-18)Concentrates
(pp. 20-21)
(pp. 20-21)- GSK Fires Drug Researcher
- Air Liquide To Buy Materials Specialist
- BASF Ups Brazilian Crop Chemicals
- Dow Flame Retardant Is Going Commercial
- Japanese Refinery Advances In Vietnam
- DuPont, Yingli Boost Solar Materials Pact
- Sasol Moves On Iranian Sell-off
- Arkema Floats A Big Boat
- Elan Rejects New Bid From Royalty Pharma
- Boehringer Slates Biologics In China
- Ash Stevens To Make Ariad Drug
- Emory University Has Drug Venture
- Pfizer Signs Pact For Drug Conjugates
- Business Roundup
ACS News
Awards(pp. 41-42)
(pp. 41-42)- Volunteer Service Award To Robert Pribush
- Lemelson-MIT Prize To Angela Belcher
- Bruce Roth Awarded 2013 Perkin Medal
- IRI Medal To Langer And Whitesides
- Women Receive International Recognition
- Kent Voorhees Receives Outstanding Faculty Award
- Rising Star Awards Seek Nominations
- Peter Mitchell Medal To Ronald Kaback
Government & Policy
Radical restructuring proposed for federal science education funding has the community scrambling
(pp. 25-28)
For 75 years, the Industrial Research Institute has been fostering collaboration among its members
(pp. 29-30)Books
Chemist argues that origin of life and Darwinian evolution are a continuum that can be linked by chemical principles
(pp. 38-39)Education
Committee on Professional Training proposes tweaks to criteria for undergraduate chemistry programs
(pp. 36-37)
Science & Technology
Microscopy points to precise color of railcar, but spectroscopy may be needed to confirm results
(p.34)
Synthesis of lanthanide(II) compounds may lead to other chemical transformations
(pp. 32-33)Concentrates(pp. 30-31)
(pp. 30-31)